Systematic Complex Haploinsufficiency-Based Genetic Analysis of <i>Candida albicans</i> Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes.

Glazier, Virginia E; Murante, Thomas; Koselny, Kristy; Murante, Daniel; Esqueda, Marisol; Wall, Gina A; Wellington, Melanie; Hung, Chiung-Yu; Kumar, Anuj; Krysan, Damian J

Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes.

Glazier, Virginia E; Murante, Thomas; Koselny, Kristy; Murante, Daniel; Esqueda, Marisol; Wall, Gina A; Wellington, Melanie; Hung, Chiung-Yu; Kumar, Anuj; Krysan, Damian J.

Afiliação

Glazier VE; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Murante T; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Koselny K; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Murante D; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Esqueda M; Department of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Wall GA; Department of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Wellington M; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Hung CY; Department of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Kumar A; Department of Molecular, Cellular and Developmental Biology, University of Michigan 48109.
Krysan DJ; Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642 damian-krysan@uiowa.edu.

G3 (Bethesda) ; 8(4): 1299-1314, 2018 03 28.

Article em En | MEDLINE | ID: mdl-29472308

Assuntos

Candida albicans/genética; Candida albicans/patogenicidade; Haploinsuficiência/genética; Fatores de Transcrição/genética; Animais; Biofilmes; Candida albicans/crescimento & desenvolvimento; Candidíase/genética; Candidíase/microbiologia; Candidíase/patologia; Modelos Animais de Doenças; Proteínas Fúngicas/genética; Proteínas Fúngicas/metabolismo; Deleção de Genes; Biblioteca Gênica; Redes Reguladoras de Genes; Heterozigoto; Fenótipo; Plâncton/metabolismo; Plasmídeos/metabolismo; Fatores de Transcrição/metabolismo; Virulência/genética

Palavras-chave

Candida albicans; biofilm formation; complex haploinsufficiency; disseminated candidiasis; haploinsufficiency; hyphal morphogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Candida albicans / Haploinsuficiência Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: G3 (Bethesda) Ano de publicação: 2018 Tipo de documento: Article

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