Tandem radical cyclization for the construction of 1-difluoroalkylated isoquinolines via Cu catalyzed and visible light-promoted pathways.
Org Biomol Chem
; 16(11): 1812-1815, 2018 03 14.
Article
em En
| MEDLINE
| ID: mdl-29473083
ABSTRACT
A Cu/B2pin2 system promoted cyclization for the synthesis of 1-difluoroalkylated isoquinolines with vinyl isocyanides and bromodifluoroacetic derivatives in moderate to good yields was reported. This method provided a mild and efficient pathway for the construction of diverse 1-difluoroalkylated isoquinolines via a proposed tandem radical cyclization process.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Ano de publicação:
2018
Tipo de documento:
Article