Your browser doesn't support javascript.
loading
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair.
Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; Light, Nicholas; Wu, Tong; LeCompte, Kimberly G; Goksenin, A Yasemin; Bunnell, Bruce A; Tabori, Uri; Shlien, Adam; Pursell, Zachary F.
Afiliação
  • Hodel KP; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, United States.
  • de Borja R; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada.
  • Henninger EE; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, United States.
  • Campbell BB; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Canada.
  • Ungerleider N; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.
  • Light N; Department of Pathology, Tulane University School of Medicine, New Orleans, United States.
  • Wu T; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada.
  • LeCompte KG; Department of Pathology, Tulane University School of Medicine, New Orleans, United States.
  • Goksenin AY; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, United States.
  • Bunnell BA; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, United States.
  • Tabori U; Department of Pharmacology, Tulane University School of Medicine, New Orleans, United States.
  • Shlien A; Tulane Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, New Orleans, United States.
  • Pursell ZF; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada.
Elife ; 72018 02 28.
Article em En | MEDLINE | ID: mdl-29488881
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / DNA Polimerase II / Reparo de Erro de Pareamento de DNA / Acúmulo de Mutações Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / DNA Polimerase II / Reparo de Erro de Pareamento de DNA / Acúmulo de Mutações Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2018 Tipo de documento: Article