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Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.
Lloyd, Katy A; Steen, Johanna; Amara, Khaled; Titcombe, Philip J; Israelsson, Lena; Lundström, Susanna L; Zhou, Diana; Zubarev, Roman A; Reed, Evan; Piccoli, Luca; Gabay, Cem; Lanzavecchia, Antonio; Baeten, Dominique; Lundberg, Karin; Mueller, Daniel L; Klareskog, Lars; Malmström, Vivianne; Grönwall, Caroline.
Afiliação
  • Lloyd KA; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Steen J; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Amara K; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Titcombe PJ; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Israelsson L; The Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Lundström SL; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Zhou D; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Zubarev RA; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Reed E; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Piccoli L; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Gabay C; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.
  • Lanzavecchia A; Division of Rheumatology, University Hospitals of Geneva, Geneva, Switzerland.
  • Baeten D; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.
  • Lundberg K; Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Mueller DL; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Klareskog L; The Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Malmström V; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
  • Grönwall C; Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.
Eur J Immunol ; 48(6): 1030-1045, 2018 06.
Article em En | MEDLINE | ID: mdl-29512823
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Região Variável de Imunoglobulina / Linfócitos B / Anticorpos Antiproteína Citrulinada / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Immunol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Região Variável de Imunoglobulina / Linfócitos B / Anticorpos Antiproteína Citrulinada / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Immunol Ano de publicação: 2018 Tipo de documento: Article