Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis.

Johnston, Daniel G W; Williams, Michelle A; Thaiss, Christoph A; Cabrera-Rubio, Raul; Raverdeau, Mathilde; McEntee, Craig; Cotter, Paul D; Elinav, Eran; O'Neill, Luke A J; Corr, Sinéad C

Johnston, Daniel G W; Williams, Michelle A; Thaiss, Christoph A; Cabrera-Rubio, Raul; Raverdeau, Mathilde; McEntee, Craig; Cotter, Paul D; Elinav, Eran; O'Neill, Luke A J; Corr, Sinéad C.

Afiliação

Johnston DGW; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Williams MA; School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland.
Thaiss CA; School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland.
Cabrera-Rubio R; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Raverdeau M; Teagasc Food Research Centre, Moorepark, Fermoy, and APC Microbiome Institute, Cork, Ireland.
McEntee C; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Cotter PD; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Elinav E; Teagasc Food Research Centre, Moorepark, Fermoy, and APC Microbiome Institute, Cork, Ireland.
O'Neill LAJ; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Corr SC; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

J Crohns Colitis ; 12(7): 835-848, 2018 Jun 28.

Article em En | MEDLINE | ID: mdl-29608690

Assuntos

Colite/genética; Colite/microbiologia; Microbioma Gastrointestinal/genética; Predisposição Genética para Doença; MicroRNAs/genética; Animais; Antibacterianos/farmacologia; Colite/induzido quimicamente; Colite/patologia; Sulfato de Dextrana; Modelos Animais de Doenças; Fezes/microbiologia; Feminino; Microbioma Gastrointestinal/efeitos dos fármacos; Deleção de Genes; Masculino; Camundongos; Fatores de Proteção; RNA Ribossômico 16S/análise

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Colite / Predisposição Genética para Doença / MicroRNAs / Microbioma Gastrointestinal Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Crohns Colitis Ano de publicação: 2018 Tipo de documento: Article

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