[Human herpesvirus-6 pneumonitis following autologous peripheral blood stem cell transplantation].
Rinsho Ketsueki
; 59(3): 300-304, 2018.
Article
em Ja
| MEDLINE
| ID: mdl-29618688
ABSTRACT
A-46-year-old man was diagnosed with peripheral T cell lymphoma, not otherwise specified. He achieved a complete remission after pirarubicin, cyclophosphamide, vincristine, and prednisolone (THP-COP) therapy and successful autologous peripheral blood stem-cell transplantation (AutoSCT). However, 6 months post AutoSCT, he complained of fever. Chest computed tomography of the patient displayed bilateral interstitial pneumonitis. Human herpesvirus-6 (HHV-6) DNA was detected in his bronchoalveolar lavage fluid. Therefore, the patient was confirmed for HHV-6 pneumonitis. The treatment with foscarnet was effective, and no relapse was noticed in the patient. Besides, we have experienced pneumonitis of unknown origin in some patients after autologous or allogeneic stem-cell transplantations. Moreover, most of the above patients were clinically diagnosed using serum or plasma markers. Therefore, examining respiratory symptoms after AutoSCT would enable a more accurate diagnosis as well as treatment of patients with HHV-6 pneumonitis.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
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Herpesvirus Humano 6
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Transplante de Células-Tronco de Sangue Periférico
Limite:
Humans
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Male
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Middle aged
Idioma:
Ja
Revista:
Rinsho Ketsueki
Ano de publicação:
2018
Tipo de documento:
Article