Activation of the Wnt/ß-Catenin Pathway by an Inflammatory Microenvironment Affects the Myogenic Differentiation Capacity of Human Laryngeal Mucosa Mesenchymal Stromal Cells.

Yang, Runqin; Yang, Xiaoshan; Liu, Shiyu; Ming, Leiguo; Zhou, Zhifei; Liang, Yuanyuan; Zhao, Yu; Zhou, Fuxing; Deng, Zhihong; Jin, Yan

Yang, Runqin; Yang, Xiaoshan; Liu, Shiyu; Ming, Leiguo; Zhou, Zhifei; Liang, Yuanyuan; Zhao, Yu; Zhou, Fuxing; Deng, Zhihong; Jin, Yan.

Afiliação

Yang R; 1 Department of Otolaryngology, Xijing Hospital, Fourth Military Medical University , Xi'an, China .
Yang X; 2 Research and Development Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Liu S; 2 Research and Development Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Ming L; 2 Research and Development Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Zhou Z; 3 State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Key Laboratory of Oral Diseases, Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Liang Y; 2 Research and Development Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Zhao Y; 3 State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Key Laboratory of Oral Diseases, Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Zhou F; 2 Research and Development Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Deng Z; 3 State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Key Laboratory of Oral Diseases, Center for Tissue Engineering, Fourth Military Medical University , Xi'an, China .
Jin Y; 1 Department of Otolaryngology, Xijing Hospital, Fourth Military Medical University , Xi'an, China .

Stem Cells Dev ; 27(11): 771-782, 2018 06 01.

Article em En | MEDLINE | ID: mdl-29644939

Assuntos

Diferenciação Celular/genética; Microambiente Celular/genética; Células-Tronco Mesenquimais/metabolismo; Desenvolvimento Muscular/genética; Via de Sinalização Wnt/genética; beta Catenina/genética; Diferenciação Celular/efeitos dos fármacos; Células Cultivadas; Microambiente Celular/efeitos dos fármacos; Expressão Gênica/efeitos dos fármacos; Humanos; Inflamação/genética; Inflamação/metabolismo; Mediadores da Inflamação/administração & dosagem; Mediadores da Inflamação/farmacologia; Peptídeos e Proteínas de Sinalização Intercelular/administração & dosagem; Peptídeos e Proteínas de Sinalização Intercelular/farmacologia; Interleucina-1beta/administração & dosagem; Interleucina-1beta/farmacologia; Mucosa Laríngea/citologia; Células-Tronco Mesenquimais/citologia; Células-Tronco Mesenquimais/efeitos dos fármacos; Desenvolvimento Muscular/efeitos dos fármacos; Fator de Necrose Tumoral alfa/administração & dosagem; Fator de Necrose Tumoral alfa/farmacologia; beta Catenina/metabolismo

Palavras-chave

differentiation; human laryngeal mucosa mesenchymal stem cells; inflammatory microenvironment; myogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Desenvolvimento Muscular / Beta Catenina / Células-Tronco Mesenquimais / Via de Sinalização Wnt / Microambiente Celular Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cells Dev Ano de publicação: 2018 Tipo de documento: Article

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