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Lipid Testing and Statin Prescriptions Among Medicaid Recipients With Systemic Lupus Erythematosus or Diabetes Mellitus and the General Medicaid Population.
Chen, Sarah K; Barbhaiya, Medha; Fischer, Michael A; Guan, Hongshu; Lin, Tzu-Chieh; Feldman, Candace H; Everett, Brendan M; Costenbader, Karen H.
Afiliação
  • Chen SK; Brigham and Women's Hospital, Boston, Massachusetts.
  • Barbhaiya M; Hospital for Special Surgery, New York, New York.
  • Fischer MA; Brigham and Women's Hospital, Boston, Massachusetts.
  • Guan H; Brigham and Women's Hospital, Boston, Massachusetts.
  • Lin TC; Brigham and Women's Hospital, Boston, Massachusetts.
  • Feldman CH; Brigham and Women's Hospital, Boston, Massachusetts.
  • Everett BM; Brigham and Women's Hospital, Boston, Massachusetts.
  • Costenbader KH; Brigham and Women's Hospital, Boston, Massachusetts.
Arthritis Care Res (Hoboken) ; 71(1): 104-115, 2019 01.
Article em En | MEDLINE | ID: mdl-29648687
ABSTRACT

OBJECTIVE:

Cardiovascular disease (CVD) risks in systemic lupus erythematosus (SLE) are similar to those in diabetes mellitus (DM). We investigated whether the numbers of lipid tests and statin prescriptions in patients with SLE are comparable with those in patients with DM and those in individuals without either disease.

METHODS:

Using Analytic eXtract files from 29 states for 2007-2010, we identified a cohort of US Medicaid beneficiaries, ages 18-65 years, with prevalent SLE. Each SLE patient was matched for age and sex with 2 patients with DM and 4 individuals in the general Medicaid population who did not have either SLE or DM. We compared the proportions of patients in each cohort who received ≥1 lipid test and ≥1 statin prescription during 1-year follow-up. We used multivariable logistic regression to calculate the odds of lipid testing and receiving prescriptions for statins and conditional logistic regression to compare the matched cohorts.

RESULTS:

We identified 3 Medicaid cohorts 25,950 patients with SLE, 51,900 patients with DM, and 103,800 Medicaid recipients without either condition. In these cohorts, lipid testing was performed in 24% of patients in the SLE group, 43% of patients in the DM group, and 16% of individuals in the group with neither condition, and statin prescriptions were dispensed in 11%, 33%, and 7% of these groups, respectively. SLE patients were 66% less likely (odds ratio [OR] 0.34, 95% confidence interval [95% CI] 0.34-0.35) to have lipid tests and 82% less likely (OR 0.18, 95% CI 0.18-0.18) to fill a statin prescription compared with DM patients. SLE patients were also less likely (OR 0.89, 95% CI 0.84-0.94) to fill a statin prescription compared with individuals in the general Medicaid population.

CONCLUSION:

Despite having an elevated risk of CVD, SLE patients received less lipid testing and received fewer statin prescriptions compared with age- and sex-matched DM patients and individuals in the general Medicaid population; this gap should be a target for improvement.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vigilância da População / Medicaid / Inibidores de Hidroximetilglutaril-CoA Redutases / Diabetes Mellitus / Lipídeos / Lúpus Eritematoso Sistêmico Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Arthritis Care Res (Hoboken) Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vigilância da População / Medicaid / Inibidores de Hidroximetilglutaril-CoA Redutases / Diabetes Mellitus / Lipídeos / Lúpus Eritematoso Sistêmico Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Arthritis Care Res (Hoboken) Ano de publicação: 2019 Tipo de documento: Article