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Suppression of Akt-mediated HDAC3 expression and CDK2 T39 phosphorylation by a bichalcone analog contributes to S phase retardation of cancer cells.
Hung, Kuang-Chen; Lin, Meng-Liang; Hsu, Shih-Wei; Lee, Chuan-Chun; Huang, Ren-Yu; Wu, Tian-Shung; Chen, Shih-Shun.
Afiliação
  • Hung KC; Department of Surgery, Division of Neurosurgery, Armed Force Taichung General Hospital, Taichung 40601, Taiwan.
  • Lin ML; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan. Electronic address: mllinsally@yahoo.com.tw.
  • Hsu SW; Department of Surgery, Division of Neurosurgery, Armed Force Taichung General Hospital, Taichung 40601, Taiwan.
  • Lee CC; Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan.
  • Huang RY; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan.
  • Wu TS; Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan.
  • Chen SS; Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan. Electronic address: sschen1@ctust.edu.tw.
Eur J Pharmacol ; 829: 141-150, 2018 Jun 15.
Article em En | MEDLINE | ID: mdl-29665367
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Chalcona / Quinase 2 Dependente de Ciclina / Proteínas Proto-Oncogênicas c-akt / Pontos de Checagem da Fase S do Ciclo Celular / Histona Desacetilases Limite: Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Chalcona / Quinase 2 Dependente de Ciclina / Proteínas Proto-Oncogênicas c-akt / Pontos de Checagem da Fase S do Ciclo Celular / Histona Desacetilases Limite: Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2018 Tipo de documento: Article