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Inorganic hydrogen polysulfides: chemistry, chemical biology and detection.
Liu, Heng; Radford, Miles N; Yang, Chun-Tao; Chen, Wei; Xian, Ming.
Afiliação
  • Liu H; Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules and College of Chemistry and Chemical Engineering, Hubei University, Wuhan, Hubei, China.
  • Radford MN; Department of Chemistry, Washington State University, Pullman, WA, USA.
  • Yang CT; Department of Chemistry, Washington State University, Pullman, WA, USA.
  • Chen W; Key Laboratory of Molecular Clinical Pharmacology, School of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Xian M; Department of Chemistry, Washington State University, Pullman, WA, USA.
Br J Pharmacol ; 176(4): 616-627, 2019 02.
Article em En | MEDLINE | ID: mdl-29669174
ABSTRACT
Recent studies suggest that inorganic hydrogen polysulfides (H2 Sn , n ≥ 2) play important regulatory roles in redox biology. Modulation of their cellular levels could have potential therapeutic value. This review article focuses on our current understanding of the biosynthesis, biofunctions, fundamental physical/chemical properties, detection methods and delivery techniques of H2 Sn . LINKED ARTICLES This article is part of a themed section on Chemical Biology of Reactive Sulfur Species. To view the other articles in this section visit http//onlinelibrary.wiley.com/doi/10.1111/bph.v176.4/issuetoc.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfetos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfetos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article