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A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants.
Luirink, Rosa A; Dekker, Stefan J; Capoferri, Luigi; Janssen, Laura F H; Kuiper, Cynthia L; Ari, Mehmet E; Vermeulen, Nico P E; Vos, J Chris; Commandeur, Jan N M; Geerke, Daan P.
Afiliação
  • Luirink RA; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Dekker SJ; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Capoferri L; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Janssen LFH; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Kuiper CL; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Ari ME; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Vermeulen NPE; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Vos JC; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Commandeur JNM; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.
  • Geerke DP; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Science, Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands. Electronic address: d.p.geerke@vu.nl.
J Inorg Biochem ; 184: 115-122, 2018 07.
Article em En | MEDLINE | ID: mdl-29723739
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Enzimático do Citocromo P-450 / Floxacilina Idioma: En Revista: J Inorg Biochem Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Enzimático do Citocromo P-450 / Floxacilina Idioma: En Revista: J Inorg Biochem Ano de publicação: 2018 Tipo de documento: Article