Amorphous ternary nanoparticle complex of curcumin-chitosan-hypromellose exhibiting built-in solubility enhancement and physical stability of curcumin.

Lim, Li Ming; Tran, The-Thien; Long Wong, Jerome Jie; Wang, Danping; Cheow, Wean Sin; Hadinoto, Kunn

Lim, Li Ming; Tran, The-Thien; Long Wong, Jerome Jie; Wang, Danping; Cheow, Wean Sin; Hadinoto, Kunn.

Afiliação

Lim LM; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637459, Singapore.
Tran TT; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637459, Singapore.
Long Wong JJ; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637459, Singapore.
Wang D; Singapore Institute of Technology, 138683, Singapore.
Cheow WS; Singapore Institute of Technology, 138683, Singapore.
Hadinoto K; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637459, Singapore. Electronic address: kunnong@ntu.edu.sg.

Colloids Surf B Biointerfaces ; 167: 483-491, 2018 Jul 01.

Article em En | MEDLINE | ID: mdl-29727835

Assuntos

Quitosana/química; Curcumina/química; Derivados da Hipromelose/química; Nanopartículas/química; Antineoplásicos/farmacologia; Sobrevivência Celular/efeitos dos fármacos; Células Cultivadas; Curcumina/farmacologia; Portadores de Fármacos/química; Células Epiteliais/efeitos dos fármacos; Mucosa Gástrica/citologia; Humanos; Microscopia Eletrônica de Varredura/métodos; Nanopartículas/ultraestrutura; Tamanho da Partícula; Solubilidade

Palavras-chave

Chitosan; Colloidal drug carrier; Curcumin bioavailability; Hypromellose; Nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curcumina / Quitosana / Nanopartículas / Derivados da Hipromelose Limite: Humans Idioma: En Revista: Colloids Surf B Biointerfaces Ano de publicação: 2018 Tipo de documento: Article

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