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Second-generation CK2α inhibitors targeting the αD pocket.
Iegre, Jessica; Brear, Paul; De Fusco, Claudia; Yoshida, Masao; Mitchell, Sophie L; Rossmann, Maxim; Carro, Laura; Sore, Hannah F; Hyvönen, Marko; Spring, David R.
Afiliação
  • Iegre J; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
  • Brear P; Department of Biochemistry , University of Cambridge , CB2 1GA , Cambridge , UK . Email: mh256@cam.ac.uk.
  • De Fusco C; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
  • Yoshida M; Structure Biophysics & FBLG , Discovery Sciences , IMED Biotech Unit , AstraZeneca , Cambridge , UK.
  • Mitchell SL; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
  • Rossmann M; R&D Division , Daiichi Sankyo Co., Ltd. , 1-2-58, Hiromachi, Shinagawa-ku , Tokyo 140-8710 , Japan.
  • Carro L; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
  • Sore HF; Department of Biochemistry , University of Cambridge , CB2 1GA , Cambridge , UK . Email: mh256@cam.ac.uk.
  • Hyvönen M; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
  • Spring DR; Department of Chemistry , University of Cambridge , CB2 1EW , Cambridge , UK . Email: spring@ch.cam.ac.uk.
Chem Sci ; 9(11): 3041-3049, 2018 Mar 21.
Article em En | MEDLINE | ID: mdl-29732088
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2018 Tipo de documento: Article