Upregulation of allograft inflammatory factor­1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.

Li, Yushu; Wang, Xingzhi; Zhang, Lei; Yuan, Xueying; Hao, Jianbing; Ni, Jie; Hao, Lirong

Upregulation of allograft inflammatory factor1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.

Li, Yushu; Wang, Xingzhi; Zhang, Lei; Yuan, Xueying; Hao, Jianbing; Ni, Jie; Hao, Lirong.

Afiliação

Li Y; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Wang X; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Zhang L; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Yuan X; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Hao J; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Ni J; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Hao L; Department of Nephropathy, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.

Int J Mol Med ; 42(2): 861-872, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29749461

Assuntos

Aldosterona/metabolismo; Proteínas de Ligação ao Cálcio/genética; Fibroblastos/patologia; Nefropatias/patologia; Rim/patologia; Macrófagos/patologia; Proteínas dos Microfilamentos/genética; Regulação para Cima; Animais; Proteínas de Ligação ao Cálcio/análise; Linhagem Celular; Fibroblastos/metabolismo; Fibrose; Rim/metabolismo; Nefropatias/genética; Nefropatias/metabolismo; Macrófagos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Proteínas dos Microfilamentos/análise; Células RAW 264.7

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação ao Cálcio / Regulação para Cima / Aldosterona / Fibroblastos / Rim / Nefropatias / Macrófagos / Proteínas dos Microfilamentos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int J Mol Med Ano de publicação: 2018 Tipo de documento: Article

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