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NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes.
Tani, Osamu; Akutsu, Yukie; Ito, Shinji; Suzuki, Takayuki; Tateishi, Yukihiro; Yamaguchi, Tomohiko; Niimi, Tatsuya; Namatame, Ichiji; Chiba, Yasunori; Sakashita, Hitoshi; Kubota, Tomomi; Yanagi, Tetsuo; Mizukami, Shusaku; Hirayama, Kenji; Furukawa, Koji; Yamasaki, Kazuhiko.
Afiliação
  • Tani O; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
  • Akutsu Y; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
  • Ito S; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Suzuki T; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Tateishi Y; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Yamaguchi T; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Niimi T; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Namatame I; Drug Discovery Research , Astellas Pharma Inc. , 21 Miyukigaoka , Tsukuba 305-8585 , Japan.
  • Chiba Y; Biotechnology Research Institute for Drug Discovery , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Umezono , Tsukuba 305-8568 , Japan.
  • Sakashita H; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
  • Kubota T; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
  • Yanagi T; Department of Immunogenetics, Institute of Tropical Medicine , Nagasaki University , 1-12-4 Sakamoto , Nagasaki 852-8523 , Japan.
  • Mizukami S; Department of Immunogenetics, Institute of Tropical Medicine , Nagasaki University , 1-12-4 Sakamoto , Nagasaki 852-8523 , Japan.
  • Hirayama K; Department of Immunogenetics, Institute of Tropical Medicine , Nagasaki University , 1-12-4 Sakamoto , Nagasaki 852-8523 , Japan.
  • Furukawa K; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
  • Yamasaki K; Biomedical Research Institute , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba 305-8566 , Japan.
J Med Chem ; 61(11): 5047-5053, 2018 06 14.
Article em En | MEDLINE | ID: mdl-29771525
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Transferases Intramoleculares / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: J Med Chem Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Transferases Intramoleculares / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: J Med Chem Ano de publicação: 2018 Tipo de documento: Article