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Acute liver injury following Garcinia cambogia weight-loss supplementation: case series and literature review.
Crescioli, Giada; Lombardi, Niccolò; Bettiol, Alessandra; Marconi, Ettore; Risaliti, Filippo; Bertoni, Michele; Menniti Ippolito, Francesca; Maggini, Valentina; Gallo, Eugenia; Firenzuoli, Fabio; Vannacci, Alfredo.
Afiliação
  • Crescioli G; Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy. giada.crescioli@unifi.it.
  • Lombardi N; Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
  • Bettiol A; Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
  • Marconi E; Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
  • Risaliti F; Division of General Medicine 2, New Hospital "Santo Stefano", Prato, Italy.
  • Bertoni M; Division of General Medicine 2, New Hospital "Santo Stefano", Prato, Italy.
  • Menniti Ippolito F; National Centre for Drug Research and Evaluation, National Institute of Health, Rome, Italy.
  • Maggini V; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Gallo E; Referring Center for Phytotherapy, Tuscany Region Careggi, University Hospital, Florence, Italy.
  • Firenzuoli F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Vannacci A; Referring Center for Phytotherapy, Tuscany Region Careggi, University Hospital, Florence, Italy.
Intern Emerg Med ; 13(6): 857-872, 2018 Sep.
Article em En | MEDLINE | ID: mdl-29802521
Herbal weight-loss supplements are sold as self-medication products, and are often used under the misconception that their natural origin guarantees their safety. Food supplements are not required to provide any benefit/risk profile evaluation before marketing; however, possible risks associated with use of herbal extracts in food supplements are becoming more and more documented in the literature. Some herbs are listed as the leading cause of herb-induced liver injury, with a severe or potentially lethal clinical course, and unpredictable herb-drug interactions. Garcinia cambogia (GC) extract and GC-containing products are some of the most popular dietary supplements currently marketed for weight loss. Here, we present four cases of acute liver failure in women taking GC extract for weight loss, and a literature review of clinical evidences about hepatic toxicity in patients taking dietary supplements containing GC extract.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Redução de Peso / Falência Hepática Aguda / Suplementos Nutricionais / Garcinia cambogia Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Intern Emerg Med Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Redução de Peso / Falência Hepática Aguda / Suplementos Nutricionais / Garcinia cambogia Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Intern Emerg Med Ano de publicação: 2018 Tipo de documento: Article