Left endocarditis, changes in the new millennium. / Endocarditis infecciosas izquierdas, cambios con el nuevo milenio.
Med Clin (Barc)
; 153(2): 63-66, 2019 07 19.
Article
em En, Es
| MEDLINE
| ID: mdl-29807860
ABSTRACT
INTRODUCTION:
a description of infective left endocarditis at the turn of the millennium.METHOD:
A multicentre prospective study into the left endocarditis using data collected from the Andalusian cohort for the study of cardiovascular infections during 1984-2014.RESULTS:
Of the 1,604 endocarditis cases collected, 382 belonged to G1 (group-1, period 1983-1999) and 1,222 to G2 (group-2, 2000-2014). Patients in the new millennium have a significantly higher mean age, have more comorbidity and concomitant diseases, and nosocomial and health-related endocarditis are more frequent, as well as complications. An increase in methicillin-resistant Staphylococcus aureus, Enterococcus sp., Gram-negative bacilli and Streptococcus bovis was noted. Regarding treatment, there is an increase in the use of cephalosporins and a decrease in penicillins; there is more surgery when admitted to hospital and less delay. Mortality stands at around 30% in both millennia. In the multivariate analysis, mortality was associated with previous millennium (G1), age, Charlson index, renal failure and septic shock, and aetiologically with Staphylococcus aureus.CONCLUSIONS:
Mortality remains stable, despite diagnostic and therapeutic improvements, because patients are older, have greater comorbidity, a closer relationship with the health care system (nosocomial) and microorganisms are more aggressive.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Endocardite Bacteriana
Tipo de estudo:
Clinical_trials
/
Observational_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
/
Es
Revista:
Med Clin (Barc)
Ano de publicação:
2019
Tipo de documento:
Article