All-optical photoacoustic Doppler transverse blood flow imaging.
Opt Lett
; 43(11): 2442-2445, 2018 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-29856399
ABSTRACT
The method of measuring blood flow in photoacoustic microscopy usually relies on ultrasonic transducers in contact fashion, which is not favored in many applications, such as wound areas, burns, and anabrosis. Here we present a noncontact photoacoustic velocity measurement method to quantitatively map transverse blood flow based on the photoacoustic Doppler (PAD) bandwidth broadening method with an all-optical photoacoustic microscopy system. It is validated that the PAD bandwidth broadening is proportional to the transverse flow within a certain range. The transverse flow speed ranging from 0 to 5.5 mm/s, as well as sectional flow images, was obtained in the blood-mimicking flow phantoms. Furthermore, the blood flow image of the mouse ear demonstrates that the all-optical photoacoustic Doppler method can acquire the information of blood flow in vivo, which could significantly broaden the scope of applications for obtaining the blood flow velocity of the microvasculature in biomedicine.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Velocidade do Fluxo Sanguíneo
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Fluxometria por Laser-Doppler
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Imagens de Fantasmas
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Orelha
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Técnicas Fotoacústicas
Limite:
Animals
Idioma:
En
Revista:
Opt Lett
Ano de publicação:
2018
Tipo de documento:
Article