Effects of clopidogrel with or without aspirin on the generation of extracellular vesicles in the microcirculation and in venous blood: A randomized placebo controlled trial.

Traby, L; Kaider, A; Kollars, M; Eichinger, S; Wolzt, M; Kyrle, P A

Traby, L; Kaider, A; Kollars, M; Eichinger, S; Wolzt, M; Kyrle, P A.

Afiliação

Traby L; Department of Medicine I, Division of Hematology and Hemostasis and Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: ludwig.traby@meduniwien.ac.at.
Kaider A; Center for Medical Statistics, Informatics and Intelligent Systems, Section for Clinical Biometrics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: alexandra.kaider@meduniwien.ac.at.
Kollars M; Department of Medicine I, Division of Hematology and Hemostasis, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: marietta.kollars@meduniwien.ac.at.
Eichinger S; Department of Medicine I, Division of Hematology and Hemostasis, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: sabine.eichinger@meduniwien.ac.at.
Wolzt M; Department of Clinical Pharmacology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: michael.wolzt@meduniwien.ac.at.
Kyrle PA; Department of Medicine I, Division of Hematology and Hemostasis, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: paul.kyrle@meduniwien.ac.at.

Thromb Res ; 167: 149-155, 2018 07.

Article em En | MEDLINE | ID: mdl-29857271

Assuntos

Aspirina/uso terapêutico; Clopidogrel/uso terapêutico; Vesículas Extracelulares/efeitos dos fármacos; Hemostasia/efeitos dos fármacos; Microcirculação/efeitos dos fármacos; Inibidores da Agregação Plaquetária/uso terapêutico; Adulto; Aspirina/farmacologia; Clopidogrel/farmacologia; Voluntários Saudáveis; Humanos; Masculino; Inibidores da Agregação Plaquetária/farmacologia

Palavras-chave

Coronary heart disease; Dual-antiplatelet therapy; Extracellular vesicles; P2Y12 inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Agregação Plaquetária / Aspirina / Vesículas Extracelulares / Clopidogrel / Hemostasia / Microcirculação Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male Idioma: En Revista: Thromb Res Ano de publicação: 2018 Tipo de documento: Article

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