Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment.

Karthikeyan, Aparna; Gupta, Neelima; Tang, Carol; Mallilankaraman, Karthik; Silambarasan, Maskomani; Shi, Meng; Lu, Lei; Ang, Beng Ti; Ling, Eng-Ang; Dheen, S Thameem

Karthikeyan, Aparna; Gupta, Neelima; Tang, Carol; Mallilankaraman, Karthik; Silambarasan, Maskomani; Shi, Meng; Lu, Lei; Ang, Beng Ti; Ling, Eng-Ang; Dheen, S Thameem.

Afiliação

Karthikeyan A; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Gupta N; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Tang C; Department of Research, National Neuroscience Institute, Singapore.
Mallilankaraman K; Duke-NUS Medical School, Singapore.
Silambarasan M; Division of Cellular and Molecular Research, National Cancer Centre, Singapore.
Shi M; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lu L; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ang BT; School of Biological Sciences, Nanyang Technological University, Singapore.
Ling EA; School of Biological Sciences, Nanyang Technological University, Singapore.
Dheen ST; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Oncotarget ; 9(38): 24950-24969, 2018 May 18.

Article em En | MEDLINE | ID: mdl-29861845

Palavras-chave

SMAD4; TGFß; glioma; microRNA-146a; microglia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Oncotarget Ano de publicação: 2018 Tipo de documento: Article

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