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Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.
Bittremieux, Mart; La Rovere, Rita M; Akl, Haidar; Martines, Claudio; Welkenhuyzen, Kirsten; Dubron, Kathia; Baes, Myriam; Janssens, Ann; Vandenberghe, Peter; Laurenti, Luca; Rietdorf, Katja; Morciano, Giampaolo; Pinton, Paolo; Mikoshiba, Katsuhiko; Bootman, Martin D; Efremov, Dimitar G; De Smedt, Humbert; Parys, Jan B; Bultynck, Geert.
Afiliação
  • Bittremieux M; Lab. Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine and Leuven Kanker Instituut, KU Leuven, Leuven, Belgium.
  • La Rovere RM; Lab. Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine and Leuven Kanker Instituut, KU Leuven, Leuven, Belgium.
  • Akl H; Lab. Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine and Leuven Kanker Instituut, KU Leuven, Leuven, Belgium.
  • Martines C; Department of Biology, Lebanese University, Hadath, Lebanon.
  • Welkenhuyzen K; Molecular Hematology Unit, ICGEB, Trieste, Italy.
  • Dubron K; Lab. Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine and Leuven Kanker Instituut, KU Leuven, Leuven, Belgium.
  • Baes M; Lab. Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine and Leuven Kanker Instituut, KU Leuven, Leuven, Belgium.
  • Janssens A; Cell Metabolism, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
  • Vandenberghe P; Department of Hematology, UZ Leuven, Leuven, Belgium.
  • Laurenti L; Department of Hematology, UZ Leuven, Leuven, Belgium.
  • Rietdorf K; Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Morciano G; Università Cattolica del Sacro Cuore, Fondazione Policlinico A. Gemelli, Rome, Italy.
  • Pinton P; School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, UK.
  • Mikoshiba K; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology and LTTA center, University of Ferrara, Ferrara, Italy.
  • Bootman MD; GVM Care & Research, Maria Pia Hospital, Torino, Italy.
  • Efremov DG; GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy.
  • De Smedt H; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology and LTTA center, University of Ferrara, Ferrara, Italy.
  • Parys JB; GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy.
  • Bultynck G; The Laboratory for Developmental Neurobiology, Brain Science Institute, RIKEN, Wako, Saitama, Japan.
Cell Death Differ ; 26(3): 531-547, 2019 03.
Article em En | MEDLINE | ID: mdl-29899382
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Linfoma Difuso de Grandes Células B / Proteínas Proto-Oncogênicas c-bcl-2 / Receptores de Inositol 1,4,5-Trifosfato Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Linfoma Difuso de Grandes Células B / Proteínas Proto-Oncogênicas c-bcl-2 / Receptores de Inositol 1,4,5-Trifosfato Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2019 Tipo de documento: Article