Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10 months of age: a <sup>13</sup>C NMR metabolomic study.

Zhou, Qi; Zheng, Hong; Chen, Jiuxia; Li, Chen; Du, Yao; Xia, Huanhuan; Gao, Hongchang

Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10 months of age: a ¹³C NMR metabolomic study.

Zhou, Qi; Zheng, Hong; Chen, Jiuxia; Li, Chen; Du, Yao; Xia, Huanhuan; Gao, Hongchang.

Afiliação

Zhou Q; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China.
Zheng H; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China. 123zhenghong321@163.com.
Chen J; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China.
Li C; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China.
Du Y; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China.
Xia H; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China.
Gao H; Institute of Metabonomics & Medical NMR, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, China. gaohc27@wmu.edu.cn.

Metab Brain Dis ; 33(5): 1661-1668, 2018 10.

Article em En | MEDLINE | ID: mdl-29946959

Assuntos

Doença de Alzheimer/metabolismo; Precursor de Proteína beta-Amiloide/metabolismo; Encéfalo/metabolismo; Glucose/metabolismo; Presenilina-1/metabolismo; Precursor de Proteína beta-Amiloide/genética; Animais; Encéfalo/efeitos dos fármacos; Modelos Animais de Doenças; Glucose/farmacologia; Espectroscopia de Ressonância Magnética; Aprendizagem em Labirinto/fisiologia; Metabolômica; Camundongos; Camundongos Transgênicos; Presenilina-1/genética

Palavras-chave

13C flux; Brain glucose; Energy metabolism; Neurodegenerative disease; Neurotransmitter

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Precursor de Proteína beta-Amiloide / Presenilina-1 / Doença de Alzheimer / Glucose Limite: Animals Idioma: En Revista: Metab Brain Dis Ano de publicação: 2018 Tipo de documento: Article

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