Notoginsenoside R1 Promotes the Growth of Neonatal Rat Cortical Neurons via the Wnt/ß-catenin Signaling Pathway.

Li, Xing-Tong; Ma, Wei; Wang, Xian-Bin; Liang, Zhang; Yang, Jin-Wei; He, Yuan; Dai, Yun-Fei; Zhang, Tong; Wang, Jia-Wei; Liu, Kuang-Pin; Wang, Xiang-Peng; Zhang, Xing-Kui; Li, Chun-Yan; Li, Jun-Jun; Tang, Hong-Yan; Su, Ping; Guo, Jian-Hui; Li, Li-Yan

Li, Xing-Tong; Ma, Wei; Wang, Xian-Bin; Liang, Zhang; Yang, Jin-Wei; He, Yuan; Dai, Yun-Fei; Zhang, Tong; Wang, Jia-Wei; Liu, Kuang-Pin; Wang, Xiang-Peng; Zhang, Xing-Kui; Li, Chun-Yan; Li, Jun-Jun; Tang, Hong-Yan; Su, Ping; Guo, Jian-Hui; Li, Li-Yan.

Afiliação

Li XT; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Ma W; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Wang XB; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Liang Z; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Yang JW; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
He Y; Second Department of General Surgery, First People's Hospital of Yunnan Province, Yunnan Kunming, China.
Dai YF; Department of Gastroenterology, First People's Hospital of Yunnan Province, Yunnan Kunming, China.
Zhang T; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Wang JW; Second Department of General Surgery, First People's Hospital of Yunnan Province, Yunnan Kunming, China.
Liu KP; Second Department of General Surgery, First People's Hospital of Yunnan Province, Yunnan Kunming, China.
Wang XP; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Zhang XK; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Li CY; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Li JJ; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Tang HY; Institute of Neuroscience, Kunming Medical University, Yunnan Kunming, China.
Su P; Department of Neurosurgery, First Affiliated Hospital of Kunming Medical University, Yunnan Kunming, China.
Guo JH; Department of Neurosurgery, First People's Hospital of Kunming City, Yunnan Kunming, China.
Li LY; Second Department of General Surgery, First People's Hospital of Yunnan Province, Yunnan Kunming, China.

CNS Neurol Disord Drug Targets ; 17(7): 547-556, 2018.

Article em En | MEDLINE | ID: mdl-29992896

Assuntos

Córtex Cerebral/citologia; Ginsenosídeos/farmacologia; Neurônios/efeitos dos fármacos; beta Catenina/metabolismo; Potenciais de Ação/efeitos dos fármacos; Potenciais de Ação/genética; Animais; Animais Recém-Nascidos; Células Cultivadas; Relação Dose-Resposta a Droga; Embrião de Mamíferos; Ginsenosídeos/genética; Ginsenosídeos/metabolismo; Proteínas Associadas aos Microtúbulos/metabolismo; Neurônios/metabolismo; Técnicas de Patch-Clamp; RNA Mensageiro/metabolismo; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; Ratos; Ratos Sprague-Dawley; Transfecção; Tubulina (Proteína)/genética; Tubulina (Proteína)/metabolismo; Proteínas Wnt/genética; Proteínas Wnt/metabolismo; Via de Sinalização Wnt/efeitos dos fármacos; beta Catenina/genética

Palavras-chave

NGR1; RNA interference; Wnt/ß-catenin signaling pathway; cortical neuron; growth; ß-catenin.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Ginsenosídeos / Beta Catenina / Neurônios Limite: Animals Idioma: En Revista: CNS Neurol Disord Drug Targets Ano de publicação: 2018 Tipo de documento: Article

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