Your browser doesn't support javascript.
loading
Impact of quantitative index derived from 123I-FP-CIT-SPECT on reconstruction with correction methods evaluated using a 3D-striatum digital brain phantom.
Furuta, Akihiro; Onishi, Hideo; Yamaki, Noriyasu; Yada, Nobuhiro; Amijima, Hizuru.
Afiliação
  • Furuta A; Department of Radiological Technology, Hiroshima Citizens Asa Hospital, 1-1, Kabeminami, Asakita-ku, Hiroshima, Hiroshima, 731-0293, Japan.
  • Onishi H; Program in Health and Welfare, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, 1-1, Gakuenmachi, Mihara, Hiroshima, 723-0053, Japan.
  • Yamaki N; Program in Health and Welfare, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, 1-1, Gakuenmachi, Mihara, Hiroshima, 723-0053, Japan. onisi@pu-hiroshima.ac.jp.
  • Yada N; Imaging Information Technology Center, Nihon Medi-Physics Co., Ltd., 2-3-12-8F, Higashi Shinagawa, Shinagawa-ku, Tokyo, 140-0002, Japan.
  • Amijima H; Department of Radiology, Shimane University Hospital, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Radiol Phys Technol ; 11(3): 294-302, 2018 Sep.
Article em En | MEDLINE | ID: mdl-30014182
ABSTRACT
We evaluated quantitation accuracy of the specific binding ratio (SBR) and specific uptake ratio (SUR) of dopamine transporter for various correction methods by using a novel three-dimensional striatum digital brain (3D-SDB) phantom comprised of segments containing the striatum, ventricle, brain parenchyma, and skull bone extracted from T2-weighted MR images. A process image was reconstructed by projection data sets with blurring, scatter, and attenuation from 3D-SDB phantom data. A 3D-iterative reconstruction algorithm was used without correction (OSEM), or with scatter (SC), attenuation (AC), AC + SC (ACSC), AC + resolution recovery (RR; ACRR), SC + RR (SCRR), AC + SC + RR (ACSCRR), AC + SC + RR + partial volume (PVC; ACSCRRP), and AC + SC + RR + PVC + ventricle (ACSCRRPV). Data were then quantified using SBR and SUR. Differences between measured and true SBR values were (in order) ACSCRR < ACSC < ACRR < AC < SCRR < SC < OSEM the maximal error was 45.3%. The trend of differences between measured and true SUR values was similar to that of SBR; maximal error was 65%. The ACSCRR-corrected SUR, which was closer to the true value, was underestimated by 30.4%. However, the ACSCRRP-corrected SUR was underestimated by a maximum of 22.5%. The SUR in the ACSCRRPV was underestimated by 6.2%. The accuracy of quantitation was improved using various types of compensation and correction. Accuracy improved more for the SUR when PVC and ventricle correction were added.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tropanos / Tomografia Computadorizada de Emissão de Fóton Único / Neostriado / Imagens de Fantasmas / Imageamento Tridimensional Idioma: En Revista: Radiol Phys Technol Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tropanos / Tomografia Computadorizada de Emissão de Fóton Único / Neostriado / Imagens de Fantasmas / Imageamento Tridimensional Idioma: En Revista: Radiol Phys Technol Ano de publicação: 2018 Tipo de documento: Article