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From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.
Ramadan, Abdulraouf M; Daguindau, Etienne; Rech, Jason C; Chinnaswamy, Krishnapriya; Zhang, Jilu; Hura, Greg L; Griesenauer, Brad; Bolten, Zachary; Robida, Aaron; Larsen, Martha; Stuckey, Jeanne A; Yang, Chao-Yie; Paczesny, Sophie.
Afiliação
  • Ramadan AM; Department of Pediatrics and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Daguindau E; Department of Pediatrics and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Rech JC; Department of Internal Medicine, Hematology and Oncology Division, University of Michigan, Ann Arbor, Michigan, USA.
  • Chinnaswamy K; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
  • Zhang J; Department of Pediatrics and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Hura GL; Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Griesenauer B; Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, USA.
  • Bolten Z; Department of Pediatrics and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Robida A; Department of Pediatrics and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Larsen M; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
  • Stuckey JA; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
  • Yang CY; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
  • Paczesny S; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
JCI Insight ; 3(14)2018 07 26.
Article em En | MEDLINE | ID: mdl-30046004
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Citocinas / Proteômica / Descoberta de Drogas / Proteína 1 Semelhante a Receptor de Interleucina-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: JCI Insight Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Citocinas / Proteômica / Descoberta de Drogas / Proteína 1 Semelhante a Receptor de Interleucina-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: JCI Insight Ano de publicação: 2018 Tipo de documento: Article