ACUTE RETINAL NECROSIS ASSOCIATED WITH HERPES ZOSTER VACCINATION.
Retin Cases Brief Rep
; 15(2): 166-168, 2021 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-30048403
ABSTRACT
PURPOSE:
To report a case of Zostavax-associated acute retinal necrosis in a patient with chronic lymphocytic leukemia.METHODS:
Case report. PATIENTS A 76-year-old white man.RESULTS:
Unilateral acute retinal necrosis with obliterative angiopathy developed in close proximity of a Zostavax vaccine. Treatment with valacyclovir hydrochloride (1 g orally three times a day) and intravitreal ganciclovir (4 mg/0.1 mL) was initiated on presentation. Because of continuous increase of the retinal necrosis, patient was switched to intravenous acyclovir (7.5 mg/kg body weight, adapted to reduced glomerular filtration rate) and given intravitreal foscarnet (2.4 mg/0.1 mL). Despite being on maximal antiviral therapy, the patient suffered a central retinal artery occlusion.DISCUSSION:
Acute retinal necrosis is a severe complication and potentially blinding disease of herpes zoster, and can occur in association with herpes zoster immunization, in particular, in immune suppressed patients.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Infecções Oculares Virais
/
Síndrome de Necrose Retiniana Aguda
/
Herpes Zoster Oftálmico
/
Vacinação
/
Vacina contra Herpes Zoster
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Retin Cases Brief Rep
Ano de publicação:
2021
Tipo de documento:
Article