Nutritional Metabolomics: Postprandial Response of Meals Relating to Vegan, Lacto-Ovo Vegetarian, and Omnivore Diets.
Nutrients
; 10(8)2018 Aug 10.
Article
em En
| MEDLINE
| ID: mdl-30103400
ABSTRACT
Metabolomics provide an unbiased tool for exploring the modulation of the human metabolome in response to food intake. This study applied metabolomics to capture the postprandial metabolic response to breakfast meals corresponding to vegan (VE), lacto ovo-vegetarian (LOV), and omnivore (OM) diets. In a cross over design 32 healthy volunteers (16 men and 16 females) consumed breakfast meals in a randomized order during three consecutive days. Fasting and 3 h postprandial serum samples were collected and then subjected to metabolite profiling using ¹H-nuclear magnetic resonance (NMR) spectroscopy. Changes in concentration of identified and discriminating metabolites, between fasting and postprandial state, were compared across meals. Betaine, choline, and creatine displayed higher concentration in the OM breakfast, while 3-hydroxyisobutyrate, carnitine, proline, and tyrosine showed an increase for the LOV and unidentified free fatty acids displayed a higher concentration after the VE breakfast. Using ¹H NMR metabolomics it was possible to detect and distinguish the metabolic response of three different breakfast meals corresponding to vegan, lacto-ovo vegetarian, and omnivore diets in serum.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dieta Vegetariana
/
Laticínios
/
Ovos
/
Metabolismo Energético
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Metabolômica
/
Refeições
/
Dieta Vegana
/
Valor Nutritivo
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Adult
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Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Nutrients
Ano de publicação:
2018
Tipo de documento:
Article