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KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.
Polson, Euan S; Kuchler, Verena B; Abbosh, Christopher; Ross, Edith M; Mathew, Ryan K; Beard, Hester A; da Silva, Bárbara; Holding, Andrew N; Ballereau, Stephane; Chuntharpursat-Bon, Eulashini; Williams, Jennifer; Griffiths, Hollie B S; Shao, Hao; Patel, Anjana; Davies, Adam J; Droop, Alastair; Chumas, Paul; Short, Susan C; Lorger, Mihaela; Gestwicki, Jason E; Roberts, Lee D; Bon, Robin S; Allison, Simon J; Zhu, Shoutian; Markowetz, Florian; Wurdak, Heiko.
Afiliação
  • Polson ES; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Kuchler VB; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Abbosh C; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Ross EM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
  • Mathew RK; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Beard HA; Department of Neurosurgery, Leeds General Infirmary, Leeds LS1 3EX, UK.
  • da Silva B; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK.
  • Holding AN; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Ballereau S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
  • Chuntharpursat-Bon E; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
  • Williams J; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Griffiths HBS; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Shao H; School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
  • Patel A; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA.
  • Davies AJ; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Droop A; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Chumas P; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Short SC; Department of Neurosurgery, Leeds General Infirmary, Leeds LS1 3EX, UK.
  • Lorger M; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Gestwicki JE; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Roberts LD; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94158, USA.
  • Bon RS; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Allison SJ; School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Zhu S; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK.
  • Markowetz F; School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
  • Wurdak H; California Institute for Biomedical Research, 11119 North Torrey Pines Road, Suite 100, La Jolla, CA 92037, USA.
Sci Transl Med ; 10(454)2018 08 15.
Article em En | MEDLINE | ID: mdl-30111643
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Tiazóis / Neoplasias Encefálicas / Glioblastoma / Metabolismo Energético Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Tiazóis / Neoplasias Encefálicas / Glioblastoma / Metabolismo Energético Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Ano de publicação: 2018 Tipo de documento: Article