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Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor.
Subhash, Vinod Vijay; Yeo, Mei Shi; Wang, Lingzhi; Tan, Shi Hui; Wong, Foong Ying; Thuya, Win Lwin; Tan, Woei Loon; Peethala, Praveen C; Soe, Mu Yar; Tan, David S P; Padmanabhan, Nisha; Baloglu, Erkan; Shacham, Sharon; Tan, Patrick; Koeffler, H Phillip; Yong, Wei Peng.
Afiliação
  • Subhash VV; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Yeo MS; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, United Kingdom.
  • Wang L; Department of Haematology-Oncology, National University Hospital, Singapore, Singapore.
  • Tan SH; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Wong FY; Department of Haematology-Oncology, National University Hospital, Singapore, Singapore.
  • Thuya WL; Department of Haematology-Oncology, National University Hospital, Singapore, Singapore.
  • Tan WL; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Peethala PC; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Soe MY; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Tan DSP; Department of Haematology-Oncology, National University Hospital, Singapore, Singapore.
  • Padmanabhan N; Department of Haematology-Oncology, National University Hospital, Singapore, Singapore.
  • Baloglu E; Department of Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
  • Shacham S; Karyopharm Therapeutics Inc, Newton, Massachusetts, USA.
  • Tan P; Karyopharm Therapeutics Inc, Newton, Massachusetts, USA.
  • Koeffler HP; Department of Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
  • Yong WP; Cancer Science Institute of Singapore, Yong loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Sci Rep ; 8(1): 12248, 2018 08 16.
Article em En | MEDLINE | ID: mdl-30115935
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Triazóis / Núcleo Celular / Proteína Supressora de Tumor p53 / Hidrazinas / Antineoplásicos Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Triazóis / Núcleo Celular / Proteína Supressora de Tumor p53 / Hidrazinas / Antineoplásicos Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article