SuPAR, an emerging biomarker in kidney and inflammatory diseases.
Postgrad Med J
; 94(1115): 517-524, 2018 Sep.
Article
em En
| MEDLINE
| ID: mdl-30177549
ABSTRACT
Soluble urokinase plasminogen activator receptor (suPAR) is a circulating form of a physiological and pathophysiological important cell surface receptor, implicated in inflammation. Recent studies showed that suPAR is a promising biomarker, useful for diagnosis, assessment and prognosis of several diseases. This review summarises the majority of preliminary studies and analyses the significance and the clinical application of suPAR in various clinical conditions. SuPAR seems to have a significant value in the diagnosis as well as prognosis of many diseases; nonetheless, it merits large-scale studies to set cut-off values that help physicians in following up their patients and accordingly tailor their treatment plans.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Receptores de Ativador de Plasminogênio Tipo Uroquinase
/
Inflamação
/
Nefropatias
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Postgrad Med J
Ano de publicação:
2018
Tipo de documento:
Article