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Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.
Clave, Emmanuel; Araujo, Itauá Leston; Alanio, Cécile; Patin, Etienne; Bergstedt, Jacob; Urrutia, Alejandra; Lopez-Lastra, Silvia; Li, Yan; Charbit, Bruno; MacPherson, Cameron Ross; Hasan, Milena; Melo-Lima, Breno Luiz; Douay, Corinne; Saut, Noémie; Germain, Marine; Trégouët, David-Alexandre; Morange, Pierre-Emmanuel; Fontes, Magnus; Duffy, Darragh; Di Santo, James P; Quintana-Murci, Lluis; Albert, Matthew L; Toubert, Antoine.
Afiliação
  • Clave E; Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, 75010 Paris, France.
  • Araujo IL; INSERM, UMRS-1160, Alloimmunity-Autoimmunity-Transplantation, 75010 Paris, France.
  • Alanio C; Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, 75010 Paris, France.
  • Patin E; INSERM, UMRS-1160, Alloimmunity-Autoimmunity-Transplantation, 75010 Paris, France.
  • Bergstedt J; Center for Translational Research, Technology Core, Institut Pasteur, 75015 Paris, France.
  • Urrutia A; Dendritic Cell Immunobiology, Department of Immunology, Institut Pasteur, 75015 Paris, France.
  • Lopez-Lastra S; INSERM, UMRS-1223, 75015 Paris, France.
  • Li Y; Human Evolutionary Genetics, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  • Charbit B; CNRS UMR-2000, 75015 Paris, France.
  • MacPherson CR; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, 75015 Paris, France.
  • Hasan M; Department of Automatic Control, Lund University, Lund SE-221, Sweden.
  • Melo-Lima BL; Center for Translational Research, Technology Core, Institut Pasteur, 75015 Paris, France.
  • Douay C; Dendritic Cell Immunobiology, Department of Immunology, Institut Pasteur, 75015 Paris, France.
  • Saut N; INSERM, UMRS-1223, 75015 Paris, France.
  • Germain M; Department of Cancer Immunology, Genentech, South San Francisco, CA 94080, USA.
  • Trégouët DA; INSERM, UMRS-1223, 75015 Paris, France.
  • Morange PE; Innate Immunity Unit, Institut Pasteur, 75015 Paris, France.
  • Fontes M; INSERM, UMRS-1223, 75015 Paris, France.
  • Duffy D; Innate Immunity Unit, Institut Pasteur, 75015 Paris, France.
  • Di Santo JP; Center for Translational Research, Technology Core, Institut Pasteur, 75015 Paris, France.
  • Quintana-Murci L; Center for Translational Research, Technology Core, Institut Pasteur, 75015 Paris, France.
  • Albert ML; Center for Translational Research, Technology Core, Institut Pasteur, 75015 Paris, France.
  • Toubert A; Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, 75010 Paris, France.
Sci Transl Med ; 10(457)2018 09 05.
Article em En | MEDLINE | ID: mdl-30185651
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Timo / Variação Genética / Receptores de Antígenos de Linfócitos T gama-delta / Receptores de Antígenos de Linfócitos T alfa-beta / Loci Gênicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Timo / Variação Genética / Receptores de Antígenos de Linfócitos T gama-delta / Receptores de Antígenos de Linfócitos T alfa-beta / Loci Gênicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Ano de publicação: 2018 Tipo de documento: Article