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Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model.
Choi, Se Hoon; Bylykbashi, Enjana; Chatila, Zena K; Lee, Star W; Pulli, Benjamin; Clemenson, Gregory D; Kim, Eunhee; Rompala, Alexander; Oram, Mary K; Asselin, Caroline; Aronson, Jenna; Zhang, Can; Miller, Sean J; Lesinski, Andrea; Chen, John W; Kim, Doo Yeon; van Praag, Henriette; Spiegelman, Bruce M; Gage, Fred H; Tanzi, Rudolph E.
Afiliação
  • Choi SH; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Bylykbashi E; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Chatila ZK; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Lee SW; Laboratoy of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Pulli B; Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Clemenson GD; Laboratoy of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Kim E; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Rompala A; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Oram MK; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Asselin C; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Aronson J; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Zhang C; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Miller SJ; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Lesinski A; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Chen JW; Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Kim DY; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • van Praag H; Department of Biomedical Science, Charles E. Schmidt College of Medicine, and Brain Institute, Florida Atlantic University, Jupiter, FL 33458, USA.
  • Spiegelman BM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Gage FH; Laboratoy of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Tanzi RE; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. tanzi@helix.mgh.harvard.edu.
Science ; 361(6406)2018 09 07.
Article em En | MEDLINE | ID: mdl-30190379
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exercício Físico / Cognição / Fator Neurotrófico Derivado do Encéfalo / Neurogênese / Doença de Alzheimer / Hipocampo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exercício Físico / Cognição / Fator Neurotrófico Derivado do Encéfalo / Neurogênese / Doença de Alzheimer / Hipocampo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article