Receiver Operating Characteristic Analysis and Clinical Trial Simulation to Inform Dose Titration Decisions.

Clements, John David; Perez Ruixo, Juan Jose; Gibbs, John P; Doshi, Sameer; Perez Ruixo, Carlos; Melhem, Murad

Clements, John David; Perez Ruixo, Juan Jose; Gibbs, John P; Doshi, Sameer; Perez Ruixo, Carlos; Melhem, Murad.

Afiliação

Clements JD; Clinical Pharmacology and Modeling & Simulation, Amgen Inc., Thousand Oaks, California, USA.
Perez Ruixo JJ; Clinical Pharmacology and Pharmacometrics, Janssen Research and Development, Beerse, Belgium.
Gibbs JP; Clinical Pharmacology and Pharmacometrics, AbbVie, North Chicago, Illinois, USA.
Doshi S; Clinical Pharmacology and Modeling & Simulation, Amgen Inc., Thousand Oaks, California, USA.
Perez Ruixo C; Clinical Pharmacology and Pharmacometrics, Janssen Research and Development, Beerse, Belgium.
Melhem M; Clinical Pharmacology, Vertex Pharmaceuticals, Boston, Massachusetts, USA.

CPT Pharmacometrics Syst Pharmacol ; 7(11): 771-779, 2018 11.

Article em En | MEDLINE | ID: mdl-30246497

Assuntos

Ensaios Clínicos como Assunto; Curva ROC; Algoritmos; Relação Dose-Resposta a Droga; Humanos; Modelos Biológicos; Farmacocinética; Farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curva ROC / Ensaios Clínicos como Assunto Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Ano de publicação: 2018 Tipo de documento: Article

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