Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.

Griner, Lesley Mathews; Gampa, Kalyani; Do, Toan; Nguyen, Huyen; Farley, David; Hogan, Christopher J; Auld, Douglas S; Silver, Serena J

Griner, Lesley Mathews; Gampa, Kalyani; Do, Toan; Nguyen, Huyen; Farley, David; Hogan, Christopher J; Auld, Douglas S; Silver, Serena J.

Afiliação

Griner LM; Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research; lesley.griner@novartis.com.
Gampa K; Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research.
Do T; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research.
Nguyen H; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research.
Farley D; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research.
Hogan CJ; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research.
Auld DS; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research.
Silver SJ; Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research.

J Vis Exp ; (139)2018 09 05.

Article em En | MEDLINE | ID: mdl-30247463

Assuntos

Avaliação Pré-Clínica de Medicamentos/métodos; Ensaios de Triagem em Larga Escala/métodos; Esferoides Celulares/efeitos dos fármacos; Antineoplásicos/farmacologia; Linhagem Celular Tumoral; Fibronectinas/metabolismo; Humanos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esferoides Celulares / Avaliação Pré-Clínica de Medicamentos / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Vis Exp Ano de publicação: 2018 Tipo de documento: Article

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