Secular Trends in the Background of Intracerebral Hemorrhage from 2010 to 2015.
J Stroke Cerebrovasc Dis
; 28(1): 26-30, 2019 Jan.
Article
em En
| MEDLINE
| ID: mdl-30297170
ABSTRACT
OBJECTIVE:
Direct oral anticoagulants (DOACs) were recently introduced for the clinical use in stroke prevention, and they are reported to show a lower risk of intracerebral hemorrhage (ICH) compared to warfarin. We were interested to know whether there is any change in clinical backgrounds of ICH patients to date.METHODS:
From 2010 to 2015, ICH patients admitted to our hospital were consecutively screened (nâ¯=â¯658). Hematoma size was assessed by brain computed tomography images on admission. Outcome was measured by the modified Rankin Scale, and favorable outcome was defined as modified Rankin Scale 0-2. Biennial trends were compared in 3 periods, P1 2010-2011, P2 2012-2013, and P3 2014-2015.RESULTS:
The percentage of ICH patients taking antithrombotics had been slightly decreasing (Pâ¯=â¯.245 [P1] 33.0%, [P2] 27.4%, and [P3] 26.2%). The frequency of patients taking antiplatelets had significantly decreased (Pâ¯=â¯.001 [P1] 50.7%, [P2] 44.3%, and [P3] 22.8%), and those taking DOACs had significantly increased (Pâ¯=â¯.001 [P1] 1.4%, [P2] 4.9%, and [P3] 19.3%). Frequency of favorable outcomes in patients taking antithrombotics was slightly increased in P3 compared to P1 and P2 (23.3%, 21.1%, and 21.3%, respectively). There was no significant difference in hematoma size between patients taking warfarin and DOACs.CONCLUSIONS:
Number of ICH patients taking antithrombotics has been slightly decreasing and the percentage taking DOACs among ICH has been increasing for 6 years.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemorragia Cerebral
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Stroke Cerebrovasc Dis
Ano de publicação:
2019
Tipo de documento:
Article