Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes.

Wei, Sheng; Li, Zifa; Ren, Meng; Wang, Jieqiong; Gao, Jie; Guo, Yinghui; Xu, Kaiyong; Li, Fang; Zhu, Dehao; Zhang, Hao; Lv, Rongju; Qiao, Mingqi

Wei, Sheng; Li, Zifa; Ren, Meng; Wang, Jieqiong; Gao, Jie; Guo, Yinghui; Xu, Kaiyong; Li, Fang; Zhu, Dehao; Zhang, Hao; Lv, Rongju; Qiao, Mingqi.

Afiliação

Wei S; Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, #4655 University Road, University Science Park, Changqing District, Jinan, 250355, China.
Li Z; Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, 250012, China.
Ren M; Laboratory of Behavioural Brain Analysis, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Wang J; Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Gao J; Laboratory of Behavioural Brain Analysis, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Guo Y; Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Xu K; Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Li F; Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, #4655 University Road, University Science Park, Changqing District, Jinan, 250355, China.
Zhu D; Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, #4655 University Road, University Science Park, Changqing District, Jinan, 250355, China.
Zhang H; Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, #4655 University Road, University Science Park, Changqing District, Jinan, 250355, China.
Lv R; Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Qiao M; Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, #4655 University Road, University Science Park, Changqing District, Jinan, 250355, China.

BMC Neurosci ; 19(1): 61, 2018 Oct 16.

Article em En | MEDLINE | ID: mdl-30326843

Assuntos

Encéfalo/metabolismo; Transtornos Cognitivos/metabolismo; Transtorno Depressivo/metabolismo; Efeitos Tardios da Exposição Pré-Natal; Estresse Psicológico; Animais; Ansiedade/etiologia; Ansiedade/metabolismo; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Transtornos Cognitivos/etiologia; Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico/metabolismo; Transtorno Depressivo/etiologia; Sacarose Alimentar; Modelos Animais de Doenças; Dominação-Subordinação; Comportamento Exploratório/fisiologia; Comportamento Alimentar/fisiologia; Feminino; Aprendizagem/fisiologia; Masculino; Fosforilação; Gravidez; Proteínas de Ligação a RNA/metabolismo; Ratos Wistar; Organismos Livres de Patógenos Específicos; Estresse Psicológico/metabolismo

Palavras-chave

Behavioural phenotype; Neurobiochemistry; Offspring; Social defeat stress; Stress before pregnancy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Estresse Psicológico / Encéfalo / Transtornos Cognitivos / Transtorno Depressivo Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: BMC Neurosci Ano de publicação: 2018 Tipo de documento: Article

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