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Cladosporin Derivatives Obtained by Biotransformation Provide Guidance for the Focused Derivatization of this Antimalarial Lead Compound.
Fredenhagen, Andreas; Schroer, Kirsten; Schröder, Harald; Hoepfner, Dominic; Ligibel, Mathieu; Porchet Zemp, Liliane; Radoch, Caroline; Freund, Ernst; Meishammer, Aldo.
Afiliação
  • Fredenhagen A; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Schroer K; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Schröder H; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Hoepfner D; Novartis Institutes for BioMedical Research, Chemical Biology and Therapeutics, Fabrikstrasse 22-3.051, Postfach, 4002, Basel, Switzerland.
  • Ligibel M; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Porchet Zemp L; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Radoch C; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Freund E; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
  • Meishammer A; Novartis Institutes for BioMedical Research, Global Discovery Chemistry WKL-122.P.37, Postfach, 4002, Basel, Switzerland.
Chembiochem ; 20(5): 650-654, 2019 03 01.
Article em En | MEDLINE | ID: mdl-30347507
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Malária Falciparum / Inibidores Enzimáticos / Isocumarinas / Descoberta de Drogas / Lisina-tRNA Ligase / Antimaláricos Tipo de estudo: Guideline Idioma: En Revista: Chembiochem Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Malária Falciparum / Inibidores Enzimáticos / Isocumarinas / Descoberta de Drogas / Lisina-tRNA Ligase / Antimaláricos Tipo de estudo: Guideline Idioma: En Revista: Chembiochem Ano de publicação: 2019 Tipo de documento: Article