Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids.

Nothisen, Marc; Perche-Létuvée, Phanélie; Behr, Jean-Paul; Remy, Jean-Serge; Kotera, Mitsuharu

Nothisen, Marc; Perche-Létuvée, Phanélie; Behr, Jean-Paul; Remy, Jean-Serge; Kotera, Mitsuharu.

Afiliação

Nothisen M; Laboratoire de Chimie Biofonctionnelle, Université de Strasbourg, CNRS, CAMB UMR 7199, LabEx MEDALIS, Faculté de Pharmacie, 67400 Illkirch, France.
Perche-Létuvée P; Laboratoire V-SAT, Université de Strasbourg, CNRS, CAMB UMR 7199, LabEx MEDALIS, Faculté de Pharmacie, 67400 Illkirch, France.
Behr JP; Laboratoire V-SAT, Université de Strasbourg, CNRS, CAMB UMR 7199, LabEx MEDALIS, Faculté de Pharmacie, 67400 Illkirch, France.
Remy JS; Laboratoire de Chimie Biofonctionnelle, Université de Strasbourg, CNRS, CAMB UMR 7199, LabEx MEDALIS, Faculté de Pharmacie, 67400 Illkirch, France. Electronic address: remy@unistra.fr.
Kotera M; Laboratoire V-SAT, Université de Strasbourg, CNRS, CAMB UMR 7199, LabEx MEDALIS, Faculté de Pharmacie, 67400 Illkirch, France. Electronic address: m.kotera@unistra.fr.

Mol Ther Nucleic Acids ; 13: 483-492, 2018 Dec 07.

Article em En | MEDLINE | ID: mdl-30388622

Palavras-chave

MCTS; SSO; carrier-free oligonucleotide delivery; cationic oligonucleotide-oligospermine conjugate; exon skipping; multicellular tumor spheroids; splice switching oligonucleotides

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2018 Tipo de documento: Article