Differential expression of TLRs 2, 4, 9, iNOS and TNF-&#945; and arginase activity in peripheral blood monocytes from glucantime unresponsive and responsive patients with anthroponotic cutaneous leishmaniasis caused by Leishmania tropica.

Oliaee, Razieh Tavakoli; Sharifi, Iraj; Afgar, Ali; Jafarzadeh, Abdollah; Kareshk, Amir Tavakoli; Bamorovat, Mehdi; Sharifi, Hamid; Babaei, Zahra; Keyhani, Amir; Keyhani, Alireza; Abedi, Leili; Sharifi, Fatemeh

Differential expression of TLRs 2, 4, 9, iNOS and TNF-α and arginase activity in peripheral blood monocytes from glucantime unresponsive and responsive patients with anthroponotic cutaneous leishmaniasis caused by Leishmania tropica.

Oliaee, Razieh Tavakoli; Sharifi, Iraj; Afgar, Ali; Jafarzadeh, Abdollah; Kareshk, Amir Tavakoli; Bamorovat, Mehdi; Sharifi, Hamid; Babaei, Zahra; Keyhani, Amir; Keyhani, Alireza; Abedi, Leili; Sharifi, Fatemeh.

Afiliação

Oliaee RT; Department of Medical Parasitology and Mycology, Kerman University of Medical Sciences, Kerman, Iran.
Sharifi I; Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran. Electronic address: iraj.sharifi@yahoo.com.
Afgar A; Research Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Jafarzadeh A; Department of Immunology, Medical School, Kerman University of Medical Sciences, Kerman, Iran.
Kareshk AT; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Bamorovat M; Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Sharifi H; HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Babaei Z; Department of Medical Parasitology and Mycology, Kerman University of Medical Sciences, Kerman, Iran; Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Keyhani A; Department of Medical Parasitology and Mycology, Kerman University of Medical Sciences, Kerman, Iran.
Keyhani A; Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Abedi L; Department of Statistics and Epidemiology, Faculty of Health, Kerman University of Medical Sciences, Kerman, Iran.
Sharifi F; Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Microb Pathog ; 126: 368-378, 2019 Jan.

Article em En | MEDLINE | ID: mdl-30399441

Assuntos

Arginase/metabolismo; Leishmania tropica/parasitologia; Leishmaniose Cutânea/imunologia; Antimoniato de Meglumina/metabolismo; Monócitos/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Receptores Toll-Like/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Adolescente; Adulto; Arginase/genética; Estudos de Casos e Controles; Criança; Pré-Escolar; Regulação para Baixo; Feminino; Expressão Gênica; Interações Hospedeiro-Parasita/imunologia; Humanos; Irã (Geográfico); Leishmania tropica/genética; Leishmania tropica/isolamento & purificação; Masculino; Monócitos/parasitologia; Óxido Nítrico Sintase Tipo II/genética; Receptor 10 Toll-Like/genética; Receptor 10 Toll-Like/metabolismo; Receptor 2 Toll-Like/genética; Receptor 2 Toll-Like/metabolismo; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/metabolismo; Receptores Toll-Like/genética; Fator de Necrose Tumoral alfa/genética; Regulação para Cima; Adulto Jovem

Palavras-chave

Arginase level; Glucantime unresponsiveness; Inflammatory mediators; Leishmania tropica; Leishmaniasis; Toll like receptors

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Arginase / Leishmania tropica / Monócitos / Fator de Necrose Tumoral alfa / Leishmaniose Cutânea / Óxido Nítrico Sintase Tipo II / Receptores Toll-Like / Antimoniato de Meglumina Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Microb Pathog Ano de publicação: 2019 Tipo de documento: Article

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