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Short communication: Activity of nisin, lipid bilayer fragments and cationic nisin-lipid nanoparticles against multidrug-resistant Staphylococcus spp. isolated from bovine mastitis.
Castelani, L; Arcaro, J R P; Braga, J E P; Bosso, A S; Moura, Q; Esposito, F; Sauter, I P; Cortez, M; Lincopan, N.
Afiliação
  • Castelani L; Institute of Animal Science, Dairy Cattle Center, Nova Odessa, São Paulo, Brazil 13380-011; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil 05508-900. Electronic address: livia_cast@yahoo.com.br.
  • Arcaro JRP; Institute of Animal Science, Dairy Cattle Center, Nova Odessa, São Paulo, Brazil 13380-011.
  • Braga JEP; Institute of Animal Science, Dairy Cattle Center, Nova Odessa, São Paulo, Brazil 13380-011.
  • Bosso AS; Institute of Animal Science, Dairy Cattle Center, Nova Odessa, São Paulo, Brazil 13380-011.
  • Moura Q; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil 05508-900.
  • Esposito F; Department of Clinical Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil 05508-900.
  • Sauter IP; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil 05508-900.
  • Cortez M; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil 05508-900.
  • Lincopan N; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil 05508-900; Department of Clinical Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil 05508-900. Electronic address: lincopan@usp.br.
J Dairy Sci ; 102(1): 678-683, 2019 Jan.
Article em En | MEDLINE | ID: mdl-30415844
ABSTRACT
Staphylococci are the main etiological agents of bovine mastitis. Bacteriocins and nanoparticles have emerged as promising alternatives for the future development of antimicrobial agents. This study evaluated the activity of the bacteriocin nisin and bicelles of the synthetic cationic lipid dioctadecyldimethylammonium bromide, alone and in combination, against multidrug-resistant Staphylococcus spp. strains isolated from bovine mastitis. In summary, cationic nisin/dioctadecyldimethylammonium bromide nanoparticles are shown to be a promising alternative for the control of mastitis caused by multidrug-resistant Staphylococcus spp.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus / Resistência a Múltiplos Medicamentos / Nanopartículas / Bicamadas Lipídicas / Mastite Bovina / Nisina Limite: Animals Idioma: En Revista: J Dairy Sci Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus / Resistência a Múltiplos Medicamentos / Nanopartículas / Bicamadas Lipídicas / Mastite Bovina / Nisina Limite: Animals Idioma: En Revista: J Dairy Sci Ano de publicação: 2019 Tipo de documento: Article