C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing.

Kalinava, Natallia; Ni, Julie Zhouli; Gajic, Zoran; Kim, Matthew; Ushakov, Helen; Gu, Sam Guoping

C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing.

Kalinava, Natallia; Ni, Julie Zhouli; Gajic, Zoran; Kim, Matthew; Ushakov, Helen; Gu, Sam Guoping.

Afiliação

Kalinava N; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: nkalinava@gmail.com.
Ni JZ; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: zni@dls.rutgers.edu.
Gajic Z; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: zoranzg323@gmail.com.
Kim M; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: mmk183@scarletmail.rutgers.edu.
Ushakov H; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: helen.ushakov@gmail.com.
Gu SG; Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: sam.gu@rutgers.edu.

Cell Rep ; 25(8): 2273-2284.e3, 2018 11 20.

Article em En | MEDLINE | ID: mdl-30463021

Assuntos

Proteínas de Caenorhabditis elegans/fisiologia; Caenorhabditis elegans/genética; Epigênese Genética; Heterocromatina/metabolismo; Histona Metiltransferases/fisiologia; Interferência de RNA; Animais; Sistemas CRISPR-Cas/genética; Proteínas de Caenorhabditis elegans/genética; Células Germinativas/metabolismo; Histona Metiltransferases/genética; Histonas/metabolismo; Lisina/metabolismo; Mutação/genética; RNA de Cadeia Dupla/metabolismo; Transcrição Gênica

Palavras-chave

CRISPR; HRDE-1; MET-2; SET-25; SET-32; epigenetic silencing; heterochromatin; nuclear RNAi; silencing establishment; transgenerational epigenetic inheritance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterocromatina / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Interferência de RNA / Epigênese Genética / Histona Metiltransferases Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article

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