GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration.

Quintino, Luis; Avallone, Martino; Brännstrom, Emil; Kavanagh, Patrick; Lockowandt, Marcus; Garcia Jareño, Patricia; Breger, Ludivine S; Lundberg, Cecilia

Quintino, Luis; Avallone, Martino; Brännstrom, Emil; Kavanagh, Patrick; Lockowandt, Marcus; Garcia Jareño, Patricia; Breger, Ludivine S; Lundberg, Cecilia.

Afiliação

Quintino L; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Avallone M; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Brännstrom E; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Kavanagh P; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Lockowandt M; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Garcia Jareño P; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Breger LS; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Lundberg C; CNS Gene Therapy, Department of Experimental Medical Science, Lund University, Lund, Sweden. Cecilia.lundberg@med.lu.se.

Gene Ther ; 26(1-2): 57-64, 2019 02.

Article em En | MEDLINE | ID: mdl-30531868

Assuntos

Terapia Genética/métodos; Fator Neurotrófico Derivado de Linhagem de Célula Glial/genética; Doença de Parkinson/terapia; Degeneração Estriatonigral/terapia; Animais; Feminino; Fator Neurotrófico Derivado de Linhagem de Célula Glial/metabolismo; Lentivirus/genética; Oxidopamina/toxicidade; Doença de Parkinson/etiologia; Ratos; Ratos Sprague-Dawley; Degeneração Estriatonigral/etiologia; Substância Negra/metabolismo; Substância Negra/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Terapia Genética / Degeneração Estriatonigral / Fator Neurotrófico Derivado de Linhagem de Célula Glial Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Gene Ther Ano de publicação: 2019 Tipo de documento: Article

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