Metformin and insulin treatment prevent placental telomere attrition in boys exposed to maternal diabetes.

Garcia-Martin, Isabel; Penketh, Richard J A; Janssen, Anna B; Jones, Rhiannon E; Grimstead, Julia; Baird, Duncan M; John, Rosalind M

Garcia-Martin, Isabel; Penketh, Richard J A; Janssen, Anna B; Jones, Rhiannon E; Grimstead, Julia; Baird, Duncan M; John, Rosalind M.

Afiliação

Garcia-Martin I; Division of Biomedicine, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom.
Penketh RJA; Department of Obstetrics and Gynaecology, University Hospital Wales, Cardiff, Wales, United Kingdom.
Janssen AB; Division of Biomedicine, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom.
Jones RE; Division of Cancer and Genetics, Cardiff School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
Grimstead J; Division of Cancer and Genetics, Cardiff School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
Baird DM; Division of Cancer and Genetics, Cardiff School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
John RM; Division of Biomedicine, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom.

PLoS One ; 13(12): e0208533, 2018.

Article em En | MEDLINE | ID: mdl-30533028

Assuntos

Diabetes Gestacional/tratamento farmacológico; Hipoglicemiantes/uso terapêutico; Insulina/uso terapêutico; Metformina/uso terapêutico; Placenta/metabolismo; Telômero/metabolismo; Adulto; Análise de Variância; Estudos de Casos e Controles; Feminino; Humanos; Masculino; Gravidez; Comportamento de Redução do Risco; Telômero/química; Encurtamento do Telômero

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Placenta / Telômero / Diabetes Gestacional / Hipoglicemiantes / Insulina / Metformina Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Pregnancy Idioma: En Revista: PLoS One Ano de publicação: 2018 Tipo de documento: Article

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