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Carrier-free nanoparticles of cathepsin B-cleavable peptide-conjugated doxorubicin prodrug for cancer targeting therapy.
Shim, Man Kyu; Park, Jooho; Yoon, Hong Yeol; Lee, Sangmin; Um, Wooram; Kim, Jong-Ho; Kang, Sun-Woong; Seo, Joung-Wook; Hyun, Soo-Wang; Park, Jae Hyung; Byun, Youngro; Kwon, Ick Chan; Kim, Kwangmeyung.
Afiliação
  • Shim MK; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; Department of Pharmacy, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Park J; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
  • Yoon HY; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
  • Lee S; Department of Pharmacy, Wonkwang University, Jeonbuk 54538, Republic of Korea.
  • Um W; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; Department of Chemical Engineering, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
  • Kim JH; Department of Pharmacy, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Kang SW; Predictive Model Research Center, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
  • Seo JW; Research Center for Safety Pharmacology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
  • Hyun SW; Research Center for Safety Pharmacology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
  • Park JH; Department of Chemical Engineering, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
  • Byun Y; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Kwon IC; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
  • Kim K; Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea. Electronic address: kim@kist.re.kr.
J Control Release ; 294: 376-389, 2019 01 28.
Article em En | MEDLINE | ID: mdl-30550940

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Pró-Fármacos / Catepsina B / Doxorrubicina / Nanopartículas / Neoplasias / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: J Control Release Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Pró-Fármacos / Catepsina B / Doxorrubicina / Nanopartículas / Neoplasias / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: J Control Release Ano de publicação: 2019 Tipo de documento: Article