A facile approach for the synthesis of nido-carborane fused oxazoles via one pot deboronation/cyclization of 9-amide-o-carboranes.
Chem Commun (Camb)
; 55(6): 830-833, 2019 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-30574956
ABSTRACT
A one pot deboronation/cyclization of 9-amide-o-carboranes for the synthesis of nido-7,8-carborane fused oxazole by cooperation of Pd(OAc)2, AgOAc and K2CO3 has been developed. A plausible mechanism involving an amide directed electrophilic palladation of the B-H bond and deboronation/cyclization process was proposed based on the successful isolation and structural characterization of the key deboronated intermediate.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Ano de publicação:
2019
Tipo de documento:
Article