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Antibiotic resistance pattern shown by various pathogens, causing infections in neonates.
Shaheryar, Zaib Ali; Rehman, Zakaur; Zaman, Muhammad; Shah, Shahid; Khan, Kashifur Rahman; Khan, Sajid Mahmood; Amjad, Muhammad Wahab; Raja, Maria Abdul Ghafoor; Zaidi, Awais Ali.
Afiliação
  • Shaheryar ZA; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
  • Rehman Z; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
  • Zaman M; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
  • Shah S; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
  • Khan KR; Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Khan SM; Faculty of Pharmacy and Alternative Medicine, Islamia University, Bahawalpur, Pakistan.
  • Amjad MW; Faculty of Pharmacy, Northern Border University, Arar, Saudi Arabia.
  • Raja MAG; Faculty of Pharmacy, Northern Border University, Arar, Saudi Arabia.
  • Zaidi AA; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
Pak J Pharm Sci ; 31(6 (Supplementary): 2743-2747, 2018 Nov.
Article em En | MEDLINE | ID: mdl-30587489
This study was schemed to comprehend the latest kaleidoscopic trends of bacterial resistance in neonatal pathogens against all those antibiotics commonly employed as empirical therapy in neonates. The methodological approach included; isolation and subsequent identification of those pathogens having caused bacterial infections in neonates, application of antibiotic sensitivity testing and finally construing the conclusion depicting patterns of antibiotic resistance by various pathogens, isolated from neonatal biological samples. Antibiotic resistance patterns was evident in gram-positive as well as in gram-negative bacteria in all the eight species identified in this study. Even antibiotic drugs which are being commonly relied upon for treating multi-resistant bacterial infections, found to be in effective against many newly emerged resistant bacteria, when used alone. Resistance Antibiotics drugs against which most prominent resistance pattern emerged include; Amikacin sulphate, Linezolid, Piperacillin / Tazobactam, Amoxicillin / Clavulanic acid, Vencomycin, Cefoperazone / Sulbactam, Ceftriaxone sodium, Ciprofloxacin, Cefixime trihydrate and Imipenem. The inferred upshot suggests that antibiotic resistance is emerging fast and ever-changing phenomenon of antibiotic resistance has significantly reduced the therapeutic space to maneuver, particularly, in treating neonatal infections.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Farmacorresistência Bacteriana / Antibacterianos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Newborn Idioma: En Revista: Pak J Pharm Sci Ano de publicação: 2018 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Farmacorresistência Bacteriana / Antibacterianos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Newborn Idioma: En Revista: Pak J Pharm Sci Ano de publicação: 2018 Tipo de documento: Article