Differential pharmacokinetic drug-drug interaction potential of eletriptan between oral and subcutaneous routes.

Patel, Harilal; Desai, Nirmal; Patel, Prakash; Modi, Nirav; Soni, Krunal; Dobaria, Nitin; Srinivas, Nuggehally R

Patel, Harilal; Desai, Nirmal; Patel, Prakash; Modi, Nirav; Soni, Krunal; Dobaria, Nitin; Srinivas, Nuggehally R.

Afiliação

Patel H; a Bioanalytical/Drug Metabolism and Pharmacokinetics Laboratory , Zydus Research Centre , Ahmedabad , India.
Desai N; b Department of Chemistry , St Xavier's College (Autonomous) , Ahmedabad , India.
Patel P; b Department of Chemistry , St Xavier's College (Autonomous) , Ahmedabad , India.
Modi N; a Bioanalytical/Drug Metabolism and Pharmacokinetics Laboratory , Zydus Research Centre , Ahmedabad , India.
Soni K; a Bioanalytical/Drug Metabolism and Pharmacokinetics Laboratory , Zydus Research Centre , Ahmedabad , India.
Dobaria N; a Bioanalytical/Drug Metabolism and Pharmacokinetics Laboratory , Zydus Research Centre , Ahmedabad , India.
Srinivas NR; c Pharmaceutical Technology Centre , Cadila Healthcare Limited , Ahmedabad , India.

Xenobiotica ; 49(10): 1202-1208, 2019 Oct.

Article em En | MEDLINE | ID: mdl-30588869

Assuntos

Pirrolidinas/farmacologia; Pirrolidinas/farmacocinética; Triptaminas/farmacologia; Triptaminas/farmacocinética; Administração Oral; Animais; Avaliação Pré-Clínica de Medicamentos; Injeções Subcutâneas; Masculino; Ratos; Ratos Sprague-Dawley

Palavras-chave

Drug-drug interactions; N-desmethyl eletriptan; bioanalysis; eletriptan; pharmacokinetics; physiologically based pharmacokinetic

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Triptaminas Limite: Animals Idioma: En Revista: Xenobiotica Ano de publicação: 2019 Tipo de documento: Article

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