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Linking (Pyr)1apelin-13 pharmacokinetics to efficacy: Stabilization and measurement of a high clearance peptide in rodents.
Onorato, Joelle M; Xu, Carrie; Chen, Xue-Qing; Rose, Anne V; Generaux, Claudia; Lentz, Kimberley; Shipkova, Petia; Arthur, Susan; Hennan, James K; Haskell, Roy; Myers, Michael C; Lawrence, R Michael; Finlay, Heather J; Basso, Michael; Bostwick, Jeffrey; Fernando, Gayani; Garcia, Ricardo; Hellings, Samuel; Hsu, Mei-Yin; Zhang, Rongan; Zhao, Lei; Gargalovic, Peter.
Afiliação
  • Onorato JM; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA. Electronic address: joelle.onorato@bms.com.
  • Xu C; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Chen XQ; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Rose AV; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Generaux C; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Lentz K; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Shipkova P; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Arthur S; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Hennan JK; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Haskell R; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Myers MC; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Lawrence RM; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Finlay HJ; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Basso M; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Bostwick J; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Fernando G; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Garcia R; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Hellings S; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Hsu MY; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Zhang R; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Zhao L; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
  • Gargalovic P; Drug Discovery, Bristol-Myers Squibb Company, Princeton, NJ, 08543-5400, USA.
Anal Biochem ; 568: 41-50, 2019 03 01.
Article em En | MEDLINE | ID: mdl-30605634
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Peptídeos e Proteínas de Sinalização Intercelular Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Anal Biochem Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Peptídeos e Proteínas de Sinalização Intercelular Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Anal Biochem Ano de publicação: 2019 Tipo de documento: Article