Development of [<sup>131</sup>I]I-EOE-TPZ and [<sup>131</sup>I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia.

Elsaidi, Hassan; Ahmadi, Fatemeh; Wiebe, Leonard I; Kumar, Piyush

Development of [¹³¹I]I-EOE-TPZ and [¹³¹I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia.

Elsaidi, Hassan; Ahmadi, Fatemeh; Wiebe, Leonard I; Kumar, Piyush.

Afiliação

Elsaidi H; Department of Oncology, Cross Cancer Institute, Faculty of Medicine and Dentistry, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada. elsaidi@ualberta.ca.
Ahmadi F; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, El Sultan Hussein St. Azarita, Alexandria 21521, Egypt. elsaidi@ualberta.ca.
Wiebe LI; Current address: Centre for Probe Development and Commercialization, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada. fahmadi@ualberta.ca.
Kumar P; Department of Oncology, Cross Cancer Institute, Faculty of Medicine and Dentistry, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada. leonard.wiebe@ualberta.ca.

Pharmaceuticals (Basel) ; 12(1)2019 Jan 01.

Article em En | MEDLINE | ID: mdl-30609671

Palavras-chave

benzotriazine-1,4-dioxide (BTDO), benzotriazine-1-monoxide (BTMO), tirapazamine (TPZ), SR 4317; hypoxia; radioiodination; radiosensitizer

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2019 Tipo de documento: Article