Leptomeningeal metastasis after effective first-generation EGFR TKI treatment of advanced non-small cell lung cancer.

Wu, Ya-Lan; Zhao, Qian; Deng, Lei; Zhang, Yan; Zhou, Xiao-Juan; Li, Yan-Ying; Yu, Min; Zhou, Lin; Zou, Bing-Wen; Lu, You; Liu, Yong-Mei

Wu, Ya-Lan; Zhao, Qian; Deng, Lei; Zhang, Yan; Zhou, Xiao-Juan; Li, Yan-Ying; Yu, Min; Zhou, Lin; Zou, Bing-Wen; Lu, You; Liu, Yong-Mei.

Afiliação

Wu YL; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China; Department of Oncology, Chengdu Shang Jin Nan Fu Hospital, West China Hospital, Sichuan University, Chengdu, China.
Zhao Q; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China; Department of Oncology, The First People Hospital of Zigong, Zigong, China.
Deng L; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Zhang Y; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Zhou XJ; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Li YY; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Yu M; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Zhou L; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Zou BW; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Lu Y; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Liu YM; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China. Electronic address: lymi75@163.com.

Lung Cancer ; 127: 1-5, 2019 01.

Article em En | MEDLINE | ID: mdl-30642536

Assuntos

Antineoplásicos/uso terapêutico; Carcinoma Pulmonar de Células não Pequenas/epidemiologia; Neoplasias Pulmonares/epidemiologia; Carcinomatose Meníngea/epidemiologia; Mutação/genética; Inibidores de Proteínas Quinases/uso terapêutico; Adulto; Idoso; Antineoplásicos/farmacologia; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Carcinoma Pulmonar de Células não Pequenas/mortalidade; Estudos de Coortes; Receptores ErbB/antagonistas & inibidores; Receptores ErbB/genética; Feminino; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/mortalidade; Masculino; Carcinomatose Meníngea/tratamento farmacológico; Carcinomatose Meníngea/mortalidade; Pessoa de Meia-Idade; Metástase Neoplásica; Prognóstico; Inibidores de Proteínas Quinases/farmacologia; Estudos Retrospectivos; Risco; Análise de Sobrevida; Resultado do Tratamento

Palavras-chave

Epidermal growth factor receptor tyrosine kinase inhibitor; Exon 19 deletion; L858R; Leptomeningeal metastasis; Non-small cell lung cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Carcinomatose Meníngea / Neoplasias Pulmonares / Mutação / Antineoplásicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lung Cancer Ano de publicação: 2019 Tipo de documento: Article

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